
Newsweek reports of a new study of 30 transgender men and women diagnosed with gender dysphoria. The researchers found what they described as 21 "rare" variants in 19 genes, in pathways in the brain associated with the sex hormone estrogen.
This may indicate an association between some gene combinations and the development of transgender identities.
There is no single "trans gene"
Every time I see an article like this, I feel a strong need to bring in the wider context. There is no transgender gene, in the same way there is not gay gene. This we know. Sexualities as well as gender identities are the end results of a complex interplay between various factors.
These researchers say the same thing to Newsweek:
The authors stressed in the study that they were not looking for a so-called "transgender gene," which might wrongly suggest that those with this gender identity are ill in some way.
[J. Graham] Theisen said gender is on a spectrum, in the same way that eye colour is. Rather, they wrote, the aim was to "understand the complexities of gender development through the lens of genetics."
A person's "gender identity is more likely the result of a complex interplay between multiple genes as well as environmental and societal factors," they said. The team acknowledged that categories like "transgender male" and "transgender female" alone aren't enough to describe individuals who don't identify as cisgender. For instance, others might identify as non-binary, or in numerous other ways.
"While, in some individuals, a single genetic variant may be sufficient to result in gender dysphoria, it does not follow that that particular variant would be necessary or sufficient to cause gender dysphoria in the population at large," they wrote.The researchers are looking to enlarge the study to include more trans people. A sample of 30 is a small one.
The potential danger of such studies
I know that some trans people argue that we should dismiss such studies altogether, as they may be used to invalidate trans people as ill or to distinguish between “real transgender people” and “trenders”. There is always a danger of that.





